This book provides students and professionals with comprehensive, accessible information to allow them to understand and critique studies as well as to apply evidence to actual patients in clinical settings. Preface, Acknowledgements, Principles of Evidence - Based Physical Therapist Practice, Evidence - Based Physical Therapist Practice, What is Evidence?, The Quest for Evidence: Getting Started, Elements of Evidence, Questions and Theories and Hypotheses, Research Design, Research Subjects, Variables and Their Measurement, Research Validity, Unraveling Statistical Mysteries, Appraising the Evidence, Appraising Evidence about Diagnostic Tests and Clinical Measures, Appraising Evidence about Interventions, Appraising Evidence about Clinical Prediction Rules, Appraising Outcomes Research, Appraising Evidence about Self - Report Outcomes Measures, Appraising Systematic Reviews and Clinical Practice Guidelines, Evidence in Practice, Patient and Client Preferences and Values, Putting It All Together, Appendices, Index.